Frequently Asked Questions

Traditional retrospective studies rely on multiple handoffs—data extraction, cleaning, code writing, statistical review, and manuscript formatting. In practice, this means:

• Data assembly: 4–8 weeks for inclusion criteria, missingness audits, and variable selection
• Statistical analysis: 8–12 weeks for regression models, validation, and figures
• Iteration & review: 4–6 weeks of revisions with co-authors and statisticians

Clinometrics condenses that workflow to a few hours. Once a dataset is connected, it automatically:

• Generates and validates cohort definitions
• Runs standardized regression or matching templates
• Outputs publication-ready tables and figures

A process that used to take 6–12 months can now be completed in under a day—with full reproducibility, audit logs, and exportable code.

Clinometrics is a platform that automates retrospective research workflows using standardized algorithms. It handles study design, variable mapping, and analysis generation — allowing researchers to focus on interpretation instead of manual coding.

Yes. Clinometrics follows a HIPAA-aligned architecture that defaults to de-identified or public datasets such as SEER, NSQIP-Public, and MIMIC. For institutional data, all processing occurs within approved, access-controlled environments. No protected health information (PHI) is stored or transmitted outside authorized domains. Every query, analysis, and export is logged with a full audit trail to ensure regulatory traceability and reproducibility.

Clinometrics is designed to operate within existing IRB and Data Use Agreement frameworks rather than replace them. When institutional data are used, each project runs within the organization's secure environment, governed by that institution's IRB approval and DUA terms. The platform automatically enforces access controls, encrypts identifiers where present, and tags all outputs with project-specific provenance—ensuring every figure, table, and regression can be traced back to its approved dataset and analytic context.

We currently support a wide range of healthcare databases, organized by category:

Registry & Quality Improvement Databases

• AAOS Registry Program
• ACS NSQIP (National Surgical Quality Improvement Program)
• ACS TQIP (Trauma Quality Improvement Program)
• ACS NTDB (National Trauma Data Bank)
• AJRR (American Joint Replacement Registry)
• FORCE-TJR
• Pediatric NSQIP
• TQIP (Trauma Quality Improvement Program)

Administrative & Claims Databases

• HCUP Family (KID, NEDS, NIS, SEDD, SID)
• KID (Kids' Inpatient Database)
• NIS (National Inpatient Sample)
• MarketScan
• Medicaid MAX
• Medicaid TAF Files
• Medical Expenditure Panel Survey (MEPS)
• Medicare Claims (Parts A/B/D)
• Optum Clinformatics Data Mart
• Premier Healthcare Database

ICU & Critical Care Databases

• MIMIC-III
• MIMIC-IV
• eICU Collaborative Research Database
• Veterans Affairs ICU Database
• Virtual PICU Database (VPS)
• Pediatric Health Information System (PHIS)

Oncology & Cancer Registries

• National Cancer Database (NCDB)
• SEER (Surveillance, Epidemiology, and End Results)
• SEER-Medicare Linked Dataset
• ASCO CancerLinQ
• Flatiron Health EHR-Derived Database

Cardiovascular Databases

• National Cardiovascular Data Registry (NCDR)
• NCDR ACTION Registry
• NCDR CathPCI Registry
• NCDR ICD Registry
• NCDR PVI Registry
• STS Adult Cardiac Database
• STS Congenital Database
• STS General Thoracic Database
• National Registry of Myocardial Infarction (NRMI)
• Get With The Guidelines–Heart Failure
• Get With The Guidelines–Resuscitation
• Get With The Guidelines–Stroke

Population Health Surveys

• NHANES (National Health and Nutrition Examination Survey)
• NHIS (National Health Interview Survey)
• BRFSS (Behavioral Risk Factor Surveillance System)

Specialty & Other Databases

• Cystic Fibrosis Foundation Patient Registry
• National Spinal Cord Injury Database (NSCID)
• National Pediatric Trauma Registry (NPTR)
• Department of Defense Trauma Registry (DoDTR)
• VA Databases
• Synthea (Synthetic Patient Data)

We are continuously expanding and always looking to add more! Contact us if you need support for a specific database.

Yes! Clinometrics includes a built-in AI Research Assistant that runs entirely offline for maximum privacy and security.

• Context-aware: The assistant automatically syncs with your current study workflow, including cohort definitions, variables, and analysis settings
• Statistical guidance: Get help with methodology questions, regression model selection, and data interpretation
• Workflow suggestions: The AI can suggest filters, variables, and analyses based on your research objectives
• Privacy-first: All processing happens locally on your machine — no data is sent to external servers

Absolutely! Clinometrics features integrated literature search capabilities:

• Real-time search: Query PubMed and Semantic Scholar directly from the platform
• Verified results: All papers include DOIs, publication details, and direct links to sources
• Paper selection: Select relevant papers to include in your manuscript's references
• Citation management: Selected papers are automatically formatted and integrated into your generated manuscript

Yes! Clinometrics supports comprehensive study sharing and collaboration features:

• Role-based access: Invite collaborators as Viewers (read-only), Commenters (can add comments), or Editors (full editing access)
• Email invitations: Share studies by entering a collaborator's email address
• Real-time sync: Changes made by editors are synchronized across all collaborators
• Access management: Study owners can modify roles or revoke access at any time

Yes! The platform includes an IRB Document Generator that creates institution-ready templates:

• NHSR determination letters: Auto-generated justification for Not Human Subjects Research status
• Exemption request drafts: Pre-filled exemption category documentation
• Protocol skeletons: Study protocol templates with methodology sections pre-populated
• PHI checklists: Comprehensive checklist of HIPAA identifiers for de-identification verification
• Data flow diagrams: Visual representation of data handling and security measures
• Export options: Download all documents in Word (.docx) or text format

Yes! Clinometrics offers AI-assisted manuscript drafting to accelerate your publication workflow:

• Abstract generation: Automatically draft structured abstracts based on your study design and results
• Introduction writing: Generate literature-informed introductions with proper context and citations
• Discussion sections: AI-assisted interpretation of findings with clinical implications
• Conclusion drafting: Summarize key findings and future directions
• Literature integration: Selected papers from your literature search are automatically cited
• DOCX export: Download your complete manuscript draft in Word format, ready for editing

Note: All AI-generated content should be reviewed and edited by the research team before submission.

The system is designed for clinicians, data analysts, and researchers using structured healthcare datasets like ACS-TQIP, NSQIP, SEER, and MIMIC. Institutional users can onboard biostatisticians for validation and reproducibility review.

Each study follows a verified algorithmic template corresponding to peer-reviewed statistical frameworks — including descriptive, comparative, regression-based, and matched analyses. Every output is reproducible and audit-ready.

Yes. Clinometrics supports custom imports from institutional databases or national registries. It automatically detects variable mappings, applies missingness logic, and standardizes categorical encoding to maintain analytic consistency.

Clinometrics never processes identifiable patient data. For institutional deployments, all processing occurs within a HIPAA-compliant environment or on anonymized datasets under appropriate data use agreements.

Absolutely. All tables, regression outputs, and visualizations can be exported in publication-ready formats (CSV, LaTeX, or Word tables). The platform also generates a reproducibility appendix for submission with manuscripts.